TRIFUNCTIONAL ANTIBODY-CYTOKINE FUSION PROTEIN FORMATS FOR TUMOR-TARGETED COMBINATION OF IL-15 WITH IL-7 OR IL-21

Trifunctional antibody-cytokine fusion protein formats for tumor-targeted combination of IL-15 with IL-7 or IL-21

Cytokines from the common gamma chain receptor family, such as IL-15, IL-21 and IL-7, show promise for cancer immunotherapy and have been incorporated individually into the Frozen Beverage Machines immunocytokine approach.However, their efficacy as monotherapy is limited.Here, we investigated the molecular design of tumor-directed trifunctional ant

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The short-term effect of surgical treatment for stress urinary incontinence using sub urethral support techniques on sexual function

OBJECTIVES: To evaluate the impact of surgical treatment of stress urinary incontinence on the sexual function of women and to identify whether such treatment can improve their sexual function and Unisex Hoodie overall quality of life.MATERIALS AND METHODS: 64 heterosexual women with such indication were studied using the Female Sexual Function Ind

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In Vivo Dosimetry for Superficial High Dose Rate Brachytherapy with Optically Stimulated Luminescence Dosimeters: A Comparison Study with Metal-Oxide-Semiconductor Field-Effect Transistors

The purpose of the study was to calibrate and commission optically-stimulated luminescence dosimeters (OSLDs) for in vivo measurements in contact-based 192Ir treatments for superficial high dose rate (HDR) brachytherapy in place of metal-oxide-semiconductor field-effect transistors (MOSFETs).Dose linearity and dose rate dependence were tested by va

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